Table 4. Diuretics (oral)

.
Initial dose
Target dose
Maximal dose
Loop Diuretics.

Furosamide (Lasix)
20-40 mg qd
as needed
240 mg bid (a)

Bumetanide (Bumex)
0.5-1.0 mg qd
as needed
10 mg qd

Torsemide (Demedex)
10-20 mg qd
as needed
80-120 mg bid
Thiazide Diuretics.

Hydrochlorothiazide
25-50 mg qd
as needed
100-200 mg qd
Thiazide-Related Diuretics.

Metolazone (Zaroxolyn) (b)
2.5-5.0 mg qd
2.5-5.0 mg 2-3 time/wk
10 mg qd
Potassium Sparing Diuretics.

Spironolactone
(See Aldosterone Antagonist section)

Triamterene, Amiloride

(Not use in HF)

(a) = oral Furosamide up to 2500 mg/day has been reported without toxicity.
(b) = Metolazone may cause significant electrolyte imbalance.

Diuretics - Drug Formulary and Pricing

Brand Name
Generic
Medica
(2002)

BCBS
(2002)
UCare
(2002)
Pref
One
(2002)
Health
Partner
Mayo
(2002)
Aetna
(2002)
PCS
(2002)
Dose/Day
(mg)
Cost/30 Days
($)
Hydrodiuril
Hydrochloro
thiazide
Y (G)
Y (G)
Y
.
Y (G)
Y (G)
Y (G)
Y (G)
25/day
100/day
2.70
6.00
Lasix
Furosemide
Y (G)
Y (G)
Y
Y (G)
Y
Y (G)
Y (G)
Y (G)
40/day
160/day
2.70
6.00
Bumex
Bumetanide
Y (G)
Y (G)
Y
Y (G)
.
Y (G)
Y (G)
Y (G)
1/day
4/day
(2x2)
8.02 (G)
27.40(G)
Demadex
Torsemide
.
.
.
.
.
Y
.
.
20/day
80/day
(40x2)
25.06
100.24
Zaroxolyn
Metolazone
Y
Y
Y
Y
Y
Y
Y
Y
2.5/day
5/day
28.12
31.95
Aldactone (a)
Spironolac-
tone
Y (G)
Y (G)
Y
Y (G)
Y
Y (G)
Y (G)
Y (G)
12.5/day
25/day
5.0
9.99

(a) = Low dose is used for neurohormonal antagonist treatment.
(G) = Generic