Diuretics (oral)

.
Initial dose
Target dose
Maximal dose
Loop Diuretics .

Furosamide (Lasix)
20-40 mg qd
as needed
240 mg bid (a)

Bumetanide (Bumex)
0.5-1.0 mg qd
as needed
10 mg qd

Torsemide (Demedex)
10-20 mg qd
as needed
80-120 mg bid
Thiazide Diuretics .

Hydrochlorothiazide
25-50 mg qd
as needed
100-200 mg qd
Thiazide-Related Diuretics .

Metolazone (Zaroxolyn) (b)
2.5-5.0 mg qd
2.5-5.0 mg 2-3 time/wk
10 mg qd
Potassium Sparing Diuretics .

Spironolactone
(See Aldosterone Antagonist section)

Triamterene, Amiloride

(Not use in HF)

(a) = oral Furosamide up to 2500 mg/day has been reported without toxicity.
(b) = Metolazone may cause significant electrolyte imbalance.

Diuretics - Drug Formulary and Pricing (Local)

Brand Name
Generic
Medica
(2004)

BCBS
(2004)
UCare
(2004)
Pref
One
(200)
Health
Partners
(2004)
Mayo
(2004)
Aetna
(2004)
PCS
(2004)
Dose/Day
(mg)
Cost/30 Days
($)
Hydrodiuril
Hydrochloro
thiazide
Y (G)
Y (G)
.
Y(G)
.
Y (G)
Y (G)
.
12.5 mg /day
13.99
Lasix
Furosemide
Y (G)
Y (G)
Y(G)
.
Y(G)
Y (G)
Y (G)
Y (G)
40 mg /day
8.99 (G)
Bumex
Bumetanide
Y (G)
Y (G)
Y(G)
.
Y(G)
Y (G)
Y (G)
Y (G)
0.5 mg /day
8.79 (G)
Demadex
Torsemide
.
.
Y(G)
.
.
Y(G)
Y(G)
.
5 mg /day
18.99 (G)
Zaroxolyn
Metolazone
Y
Y(G)
Y(G)
Y
Y(G)
Y(G)
Y(G)
Y(G)
2.5 mg /day
32.99 (G)
Aldactone (a)
Spironolac-
tone
Y (G)
Y (G)
Y(G)
.
Y(G)
Y (G)
Y (G)
Y (G)
25 mg /day
9.99 (G)

(a) = Low dose is used for neurohormonal antagonist treatment.
Y = Formulary.   (G) = Generic