Drugs interact with warfarin, adapted from MicroMedex. (Updating)

Level	Generic	Trade Name	Mecha nism	Class	Doc	On set	Cha nge	Inc	Dec
AAA	AAAAAAAAAA	AAAAAAAAAAAAAAA	AAA	AAAAAAAAA	AA	AA	AA	AA	AA
1	Abciximab	Reopro	G	.	F	R		Y
2	Acarbose	.	U	.	P	D		Y
2	Acemetacin	.	E	.	P	D		Y
CC1	17 Alkylated testostero	.	.	Steroid, anabo lic	.	.		Y
CC	6 Mercaptopurine	.	.	Oncology, alkylate	.	.		.	Y
2	Acetominaphen	Tylenol, Panadol, Tem pra	F	Analgesic	G	D.		Y
2	Alclofenac	.	E	.	P	D		Y
2	Alcohol	.	F	Alcohol	F	D		Y	Y
2	Allopurinol	Zyloprim, Purinol	U	Gout Rx	P	D		Y
1	Alteplase	Activase	G	.	F	R		Y
2	Aminoglutethimide	Cytraden	F	Steroid Rx	F	D		Y
CC2	Aminoglycosides	Amikacin(Amikin), Gentamycin (Geramycin) Kanamycin( Kantrex), Netimycin( Netromycin), Spectinomycin(Trobycin) Streptomycin, Tobramycin(Nebcin)	.	Antibiotic	.	.		.	Y
CC	Aminosalicylic acid	Paser	.	.	.	.		Y
2	Amiodarone	Cordarone, Pacerone	F	Antiarrhythmic	E	D		Y
2	Amitriptyline	.	A,F	.	F	D		Y
2	Amobarbital	.	F	Barbiturate	E	D		.	Y
2	Amoxapine	.	A,F	.	F	D		Y
2	Amprenavir	.	F	.	P	D		Y
0	Antacid	.	.	.	.	.
2	Apazone	.	D	.	P	D		Y
2	Aprobarbital	.	F	.	G	D			Y
2	Argatroban	.	M	.	P	D		Y
0	Ascorbic acid	.	.	.	.	.
1	Aspirin, ASA	Anacin, Ascriptin, Alka-Seltzer, Allerest, Aspergum, Bromo-Seltzer, Bufferin, Congestin, Coricidin, Cough/cold remedies, Darvon compound, Dristan E aspirin, Ecotrin, Empirin compound, Excedrin, Fiorinol, Fizrin, Nytol, Pepto-Bismol, Percodan, Sominex, Vanquish, Zactrin, Zorprin, others.	D,F	Analgesic	E	D		Y
0	Atorvastatin	.	.	.	.	.
2	Azathioprine	Imuran	A,F	Immunosuppres sion	P	D		.	Y
2	Azithromycin	Zithromax	F	Antibiotic	F	D		Y
.
0	Benazepril	.	.	.	.	.
2	Benoxaprofen	.	E	.	F	D		Y
2	Benzbromarone	.	F	.	G	D		Y
2	Bicalutamide	.	D	.	P	D		Y
2	Bismuth subsalicy late	.	D	.	F	D		Y
2	Bivalirudin	.	U	.	P	D		Y
1	Boldo	.	U	.	P	D		Y
2	Bosentan	.	F	.	F	R			Y
2	Bromfenac	.	E	.	P	D		Y
2	Bufexamac	.	E	.	P	D		Y
2	Butabarbital	Butisol	F	Barbiturate	E	D			Y
2	Butalbital	Fiorinal, (more)	F	Barbiturate	G	D			Y
.
Level of interaction: 1 = Strong, 2 = Moderate, 3 = Mild, CC = Need update, Mechanism of interaction: A = Absorbtion, B = Clearance, C = Induction, D = PB replacement, E = Platelet aggregation, F = Metabolism alteration, G = Additive, H = Decrease synthesis, M = Miscellaneous, U = Unknown. Documentation E= Exellent, G = Good, F = Fair, P = Poor. . Onset of interaction ( R = Rapid, D = Delay}, Change Warfarin dosage change. Increase INR. Decrease INR

 

Level	Generic	Trade Name	Mecha- nism	Class	Doc	On set	Cha nge	Inc	Dec
AAA	AAAAAAAAAA	AAAAAAAAAAAAAAA	AAA	AAAAAAAAA	AA	AA	AA	AA	AA
2	Calcium channel blockers	.	G	.	P	D		Y
0	Candesartan	.	.	.
1	Capecitabine	Xeloda	U	.	F	D		Y
2	Capsaicin		E	.	F	R		Y
2	Carbarmazepine	Tegatrol	F	Anticonvulsant	F	D			Y
2	Carprofen	.	E	.	P	D		Y
2	Castor oil	.	A	.	P				Y
2	Cefamandole	Mandol	E,H	Antibiotic	F	D		Y
2	Cefazolin	Ancef, Kefzol	H	Antibiotic	F	D		Y
2	Cefoperazone	Cefobid	E,H	Antibiotic	F	D		Y
2	Cefoperazone/ sulbactam	.	E	.	F	D		Y
2	Cefotetan	Cefotan	E,H	Antibiotic	P	D		Y
CC	Cefoxitin	Mefoxin	.	Antibiotic		.		Y
CC	Ceftriaxone	Rocephin	.	Antibiotic		.		Y
2	Celecoxib	Celebrex	F	Cox 2 inhibitor	E	D		Y
0	Cerivastatin	.	.	.
CC2	Cephalosporins	.	.	Antibiotic		.		Y
3	Chamomile	.	G	.	P	D		Y
CC	Chenodiol	.	.	.		.		Y
CC	Chlopropamide	Diabenese	.	Diabetic		.		Y
2	Chloral hydrate	Noctec	D	Hypnotic	P	R		Y
2	Chloramphenicol	Chloromycetin	F	Antibiotic	F	D		Y
2	Chlordiazepoxide	Libruim	U	Antianxiety	P	D			Y
2	Chlordiazepoxide / Amitriptyline	.	U	.	P	D
0	Chlorothiazide	.	.	.
2	Chloroguanide	.	U	.	P	D		Y
2	Chlorotrianisene	.	U	.	P	D			Y
2	Chlorpromazine	.	U	.	P	D
?	Chlorthalidone	Hygroton	.	Diuretic	P		.		Y
2	Cholestyramine	Questran	A	Lipid Rx	G	D			Y
0	Cilostazol	.	.	.
2	Cimetidine	Tagamet	F	Ulcer, H2 blocker	E	D		Y
2	Ciprofloxacin	Cipro	U	Antibiotic	P	D		Y
2	Cisapride	.	U	.	P	D		Y
2	Clarithromycin	.	F	.	F	D
2	Clofibrate	.Astromid-S	U	Lipid Rx	E	D		Y
2	Clomipramine	.	A,F	.	F	D		Y
2	Clopidogrel	.	G	.	P	D		Y
2	Cloxacillin	.	U	.	P	D		Y
1	Coenzyme Q10	.	Vit K2	.	P	D			Y
0	Colestipol	Cholestid	.	Lipid Rx		.
2	Cotrimoxazole	.	D,F	.	G	D		Y
CC	Contraceptives, oral	.	.	Contraceptive		.	.		Y
CC	Corticotropin	.	.	Steroid, adreno		.			Y
CC	Cortisone	.	.	Steroid, adreno		.		.	Y
2	Curcumin	.	E	.	P	D		Y
CC	Cyclophospha mide	Cytoxan	.	Oncology		.		Y	Y
0	Cycloserine	.	.	.
2	Cyclosporine	Sandimmune, Neoral	U	Immunosup pression	P	D			Y
.
Level of interaction: 1 = Strong, 2 = Moderate, 3 = Mild, CC = Need Update. Mechanism of interaction: A = Absorbtion, B = Clearance, C = Induction, D = PB replacement, E = Platelet aggregation, F = Metabolism alteration, G = Additive, H = Decrease synthesis, M = Miscellaneous, U = Unknown. Documentation E= Exellent, G = Good, F = Fair, P = Poor. . Onset of interaction ( R = Rapid, D = Delay}, Change Warfarin dosage change. Increase INR. Decrease INR

 

Level

Generic